Dateline reporter Dennis Murphy described the mastermind of the gruesome plot to kill young parents Josh Niles and Amber Washburn as "perhaps the most villainous killer" he's ever come across.
Lissa Yellow Bird spent years tracking down missing Indigenous women, until one day her own niece Carla Yellow Bird disappeared, sparking a very personal mission to bring her back home.
Amy Mihaljevic had agreed to meet a man she believed worked with her mom to buy her a special present when she disappeared in October of 1989. Detectives are hoping someone has the key to solving the mysterious case.
Dean "Dino" Pantazes and his wife Clara appeared to have the perfect marriage, but Dino was leading a secret double life that he'd stop at nothing to protect.
Kathleen Peterson was found at the bottom of the staircase in her lavish North Carolina home in 2001, but the mystery around her death continues to endure.
Maple Batalia, a beautiful 19-year-old college student, was on the cusp of realizing her dreams when she was shot and stabbed to death after leaving her campus library.
Terry Rouse grew up with a tight-knit family, but when the 24-year-old disappeared suspicions that the disappearance could have been caused by one of their own broke the family apart.