Friends say Karen Swift wasn't having a good time at a country club Halloween party in Dyersburg, Tennessee. The next morning, she went missing from her home.
Friends Carol Marlin and Margaret (Maggie) Ginn were found dead after meeting for dinner in Marietta, Georgia. But it would take the murder of Kasi Peek, years later, for the crimes to be solved.
Boston police officer John O'Keefe was found dead lying in the snow after a night of heavy drinking. His girlfriend at the time is accused of murder and reversing her car into him.
Keri Murphy, 16, called police to report a break-in at her family's Humble, Texas, home. Her mom Mary Ann Murphy was found murdered, leading to stunning revelations.
After a young father was murdered and a woman was stabbed to death in broad daylight, law enforcement had to determine whether the two crimes could be connected.
"None of it felt real," Aya Altantawi said of finding her mom, Nada Huranieh, dead on the patio of their sprawling Michigan home — and the shocker that came next.
After LaNell Barsock was found dead in her Palmdale home's garage with a plastic bag over her head, detectives eventually realized their investigation was "heading in the wrong direction."
When two women were killed in the same Arlington, Texas apartment complex in the same year, panic spread through the city. “He said, ‘Don’t scream and I won’t kill you,'" one survivor recalled.