Cash App founder Bob Lee’s fatal stabbing in San Francisco sparked talk of a possible random robbery gone wrong, but police and his loved ones almost immediately suspected that wasn't the case.
After an elderly socialite vanished from her New York City brownstone, Sante Kimes and her son Kenny were arrested, revealing decades of crime, deception and murder.
After Gary “Big Daddy” Farris disappeared, his remains were found on his family's estate in Alpharetta, Georgia, kicking off an investigation that unveiled "greed"-motivated family rifts.
New developments related to Erik and Lyle Menendez's murder conviction have put their chances at freedom closer, and widespread backlash about the case has prompted prosecutor Pamela Bozanich to arm herself.
Friends say Karen Swift wasn't having a good time at a country club Halloween party in Dyersburg, Tennessee. The next morning, she went missing from her home.
Friends Carol Marlin and Margaret (Maggie) Ginn were found dead after meeting for dinner in Marietta, Georgia. But it would take the murder of Kasi Peek, years later, for the crimes to be solved.
Boston police officer John O'Keefe was found dead lying in the snow after a night of heavy drinking. His girlfriend at the time is accused of murder and reversing her car into him.
Keri Murphy, 16, called police to report a break-in at her family's Humble, Texas, home. Her mom Mary Ann Murphy was found murdered, leading to stunning revelations.
After a young father was murdered and a woman was stabbed to death in broad daylight, law enforcement had to determine whether the two crimes could be connected.
"None of it felt real," Aya Altantawi said of finding her mom, Nada Huranieh, dead on the patio of their sprawling Michigan home — and the shocker that came next.
After LaNell Barsock was found dead in her Palmdale home's garage with a plastic bag over her head, detectives eventually realized their investigation was "heading in the wrong direction."
When two women were killed in the same Arlington, Texas apartment complex in the same year, panic spread through the city. “He said, ‘Don’t scream and I won’t kill you,'" one survivor recalled.
A key witness in the case against Victor Paleologus breaks her silence in a two-hour special based on Dateline's hit podcast, Murder in the Hollywood Hills.